In a dystopian future where science has become illegal, players take on the role of a witty rogue scientist named Dr. P. H. Doodles, who finds themselves in the middle of a bizarre competition to claim a legendary underground laboratory. Players traverse quirky locations, from a mad alchemist's mausoleum to a sentient library guarded by overly-enthusiastic bookworms. They encounter eccentric NPCs, solve quirky puzzles involving makeshift inventions, and have to make moral choices about the experiments they propose to undertake, all while gathering a team of misfit lab assistants. The gameplay is driven by player choices, allowing for multiple endings that shift based on the player's ethical stance and quirky inventions.