In 'Whose Heart Is It, Anyway?', players step into the shoes of a quirky heart-transplant surgeon who discovers a peculiar phenomenon: upon performing heart transplants, patients exhibit bizarre behaviors reflective of their donors' personalities. The player must navigate through a series of chaotic situations, unraveling the mystery of donor and recipient bonds while maintaining their sanity in a hospital filled with eccentric characters. Choices about treatment plans, interactions with the peculiar patients, and dilemmas of ethical surgery lead to a variety of dramatic and comedic outcomes, ultimately unveiling the truth behind every heart they handle.