In 'Math Mastermind: The AI Tutor', players take on the role of a student who must navigate through challenging math problems with the help of Khanmigo, the AI tutor. As Khanmigo guides and assists the student in various mathematical concepts, the player must solve equations, fractions, and calculus problems to progress through levels and enhance their math skills. The game focuses on immersive learning through interactive gameplay, making math fun and engaging for all players.