In 'Lab Rats: The Great Lab Heist', players assume the roles of sentient lab rats who have discovered their intelligence and are plotting a daring escape from the eccentric scientist's laboratory that has been their prison. Each rat possesses unique abilities gleaned from the bizarre experiments they’ve endured, such as enhanced agility, explosive flatulence, or ultra-keen senses. Players will navigate a sprawling, zany lab setting, solving puzzles, navigating obstacles, and using their powers in humorous ways to outsmart the lab's defenses. As they interact with wacky lab equipment and eccentric robot assistants, they'll uncover the dark secrets of the lab and the ridiculous experiments that happened there, ultimately leading to the thrilling heist to reclaim their freedom and uncover their true origins.