In a secret underground research facility, you play as one of the highly intelligent lab rats, subjected to mind-altering experiments. The laboratory is filled with quirky scientists, malfunctioning machinery, and other genetically enhanced creatures. As tensions rise and experiments go awry, you must gather allies, navigate treacherous environments, and uncover a sinister plot threatening both rats and humans. Your choices throughout the game will affect the outcome of your rebellion against the oppressive scientists, leading to multiple hilarious and dramatic endings.