In a secretive underground lab, a group of genetically enhanced lab rats finds themselves in a chaotic power struggle after an experimental formula grants them heightened intelligence. Players take on the role of Scritch, a clever and rebellious rat who must navigate the treacherous hierarchy of the lab, form alliances with other animals, and outsmart both the scientists and rival lab specimens. Choices made by the player drive the storyline, leading to multiple endings based on alliances formed, betrayals executed, and quests completed as they seek to overthrow the current regime led by an overbearing guinea pig with delusions of grandeur.