In Immune Trace Hunter, players must use their strategic thinking and problem-solving skills to help a team of scientists identify the presence of immune traces in T cell receptors from patients. By analyzing snippets of 4-residue long strips from different CDR3s of T cell receptor sequences, players must calculate the frequency and score of each snippet to determine the presence or absence of immune traces. The game is a fast-paced, brain-teasing adventure that will leave players entertained and intrigued.