In 'Hello, Who's This Anyway?', you play as Sam, an overly curious private detective who specializes in solving bizarre phone calls. One day, you receive a series of mysterious calls from random people, claiming to be from different dimensions. As you navigate through humorous and absurd scenarios, you must interact with bizarre characters, solve quirky mysteries, and piece together the truth behind these otherworldly calls. Each interaction leads you to strange worlds, where you gather clues and use your wit to figure out who's really on the other end of the line, while also delivering clever punchlines along the way.