In 'Chrono Crisis: Time's Last Laugh', players assume the role of a cynical time-traveling stand-up comedian who discovers that reality is being rewritten by a villainous time manipulator trying to erase comedy from existence. As players navigate through various historical eras—from ancient Rome to the Roaring Twenties—they must utilize humor and wit to outsmart time paradoxes, interact with famous figures, and gather allies from different epochs. Choices made throughout the game affect not only the outcome but also the punchlines, with each decision influencing the comedic performance and ultimate fate of time itself.